Посты с тэгом: Stable


  • Vitamin C — The most advanced technology to stabilize antioxidants

    2 комментария / Опубликовано 111111111 11111111111111

    PHYTIC [TC] SERUM:  A UNIQUE AND STABLE MOLECULAR COMBINATION  

      8% L-ASCORBIC ACID (vitamin C in its natural form)

    • Skin surface: boosts epidermical cells turnover to enhance skin radiance and refine skin texture.
    • At dermis level: significantly increases collagen and dermis component synthesis (1,2,3) to reduce wrinkles and improve skin structure.
    • One of the most powerful antioxidants to protect skin cells against external agressions (UV, stress, pollution,…). This makes L-Ascorbic Acid a must-have to prevent skin aging.
    • Anti-spot activity thanks to its antioxidant action and limitation of melanin transfer by the weakening of dendrites (4).

    2% PHYTIC ACID

    • Powerful antioxydant and anti-cancer (5)
    • Anti pollution (chelates iron and scavengers heavy metals)
    • Regulates pigmentation and normalises skin sebum rate (6)
    • Synergistic stabilization action with L-ascorbic acid.

    0,2% TANNIC ACID

    • Powerful antioxidant, neutralises pro-oxydative Fenton reaction (7)
    • Chelates iron and anti-pollution effect
    • Stimulates collagen synthesis

      

    COMPARATIVE TECHNIQUES  TO STABILIZE L-ASCORBIC ACID (VITAMIN C)

    L-ascorbic acid (vitamin C in its natural form) is highly unstable in contact with air and water oxygen, especially with warm temperature.
    Different techniques are used to stabilize it with unequal results.

      

    ADVANTAGES

    DISADVANTAGES

      

    ALPHASCIENCE TECHNOLOGY

    BIOMIMETISM — INSPIRED BY NATURE

    Molecular combination of L-ascorbic acid with powerful antioxidants.

    Excellent stability in the skin and with heat.
    Efficiency and bioavailability.

    Complex formulas

    Encapsulated L-ascorbic acid

    Easy to formulate

    Limited to medium concentrations (3 to 4%).

    Low stability.

    Vitamin C derivatives (ascorbosilane, sodium ascorbyl phosphate, etc)  

    Easy to formulate  

    Low anti-aging and antioxidant efficiency.

    Dry form of L-ascorbic acid (powder) to mix with a solution before use.

    Easy to formulate.

    Stable before mixing.

    No guarantee of stability after mixing.
    Weak penetration. Uneasy for patient.

      

    BIOMIMETISM: ALPHASCIENCE IS INSPIRED BY NATURE TO STABILIZE ANTIOXIDANTS  

    How do fruits which contain a lot of water manage to keep their vitamin C and antioxidants content stable and active?

    L-ascorbic acid (vitamin C in its natural form) is fully stable in an orange for example, because it is associated with other antioxidants such as polyphenols and flavonoids.
    This assemblage forms a complex chemical structure that is totally stable dynamically.  
      

    ALPHASCIENCE STABLE MOLECULAR COMBINATION

    By observing nature and thanks to our control of the chemical interactions between antioxidants and Vitamin C, we developed a unique associative complex of powerful antioxidants which ensures the stabilization of highly concentrated L-ascorbic acid.  

    FOR THE 1ST TIME: STABILIZATION EVIDENCE AT HIGH TEMPERATURE

    Evolution of L-Ascorbic Acid concentration in Alphascience serum
    HPLC mesures by an indépendant laboratory (SGS Multilab)

     

    Bibliography:

    1. Nusgens BV, Humbert P, Rougier A, et al. Topically applied vitamin C enhances the mRNA level of collagens I and III, their proces- sing enzymes and tissue inhibitor of matrix metalloproteinase 1 in the human dermis J Invest Dermatol 2001; 116 : 853-859
    2. Stimulation of collagen gene expression by ascorbic acid in cultured human fibroblasts. A role for lipid peroxidation? M Chojkier, K Houglum, J Solis-Herruzo and D A Brenner
    3. Ascorbic acid enhances the expression of type 1 and type 4 collagen and SVCT2 in cultured human skin fibroblasts. Y Kishimoto, N Saito, K Kurita, K Shimokado
    4. Marta I. Rendon MD, Jorge I. Gaviria MD — Review of Skin-Lightening Agents — Dermatologic Surgery
    5. Crit Rev Food Sci Nutr. 1995 Nov;35(6):495-508. Phytic acid in health and disease. Zhou JR1, Erdman JW Jr.
    6. Dr Zhong, Soongsil University
    7. Polyphenol tannic acid inhibits hydroxyl radical formation from Fenton reaction by complexing ferrous ions. George K.B. Lopes, Herbert M. Schulman, Marcelo Hermes-Lima

     

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  • Tannic Acid — A breakthrough antioxidant

    0 комментарий / Опубликовано 111111111 11111111111111

    A breakthrough antioxidant

    Where does the tannic acid come from?

    Tannic acid is a polyphenol of the family of tannins. It is present in many plants, especially oak bark, yew or Tynanthus panurensis. It is found in all parts of the plant, seeds, gall, cones and woods.

    Tannic acid is present in high concentration in the bark and the wood of Sequoia to protect it from diseases, parasites and fungi, this explains its exceptional lifespan: some sequoia specimens may well exceed 3,000 years.

    Although many trees contain some tannin, the high content in Sequoias and its cinnamon colour is the reason why the latter are often called “Redwoods”.

    How did Alfred Marchal discover the tannic acid?

    By analysing hundreds of polyphenols issued from nature and screening hose who had protective capacity superior to reference antioxidants, Alfred Marchal realized that tannic acid is highly efficient in anti-aging and anti-pollution treatments, with the many outstanding properties:

    • Protective capacity superior to reference antioxidants
    • Protects the endothelium of blood vessels, which explains his efficiency to treat bruises and redness
    • Inhibits degradation of collagen
    • Effective against skin tumors
    • Inhibits advanced glycation
    • Antifungal and antibacterial activities
    • It inhibits Fenton Reaction by complexing Fe3+

     

    What is unique in Alphascience use of tannic acid?

    As most polyphenols and antioxidants, Tannic acid is highly unstable.

    For the first time, Alphascience managed to stabilize tannic acid and use it in high concentration in its formulations to protect, restore and maintain the integrity of skin cells for exceptional protective results.

    Tannic Acid is highly synergistic with Vitamin C (L-ascorbic acid) and empowers its antioxidant activity.

    Alphascience is the only company in the world to master the manufacturing process to achieve the right chemical interaction between the Tannic Acid and Vitamin C and make the most of their unique anti- aging and anti-pollution properties.

     

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